Open AccessPIG KIDNEY TRANSPLANTATION IN BABOONS: Anti-Gal??1-3Gal IgM Alone Is Associated with Acute Humoral Xenograft Rejection and Disseminated Intravascular Coagulation1
Author(s) -
Léo Bühler,
Kazuhiko Yamada,
Hiroshi Kitamura,
Ian Alwayn,
M. Basker,
James Z. Appel,
Robert B. Colvin,
Mary E. WhiteScharf,
David H. Sachs,
Simon C. Robson,
Michel Awwad,
D. K. C. Cooper
Publication year - 2001
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200112150-00007
Subject(s) - medicine , transplantation , histology , kidney , immunosuppression , xenotransplantation , kidney transplantation , pathology , immunology
Kidneys harvested from miniature swine or pigs transgenic for human decay-accelerating factor (hDAF) were transplanted into baboons receiving an anti-CD154 monoclonal antibody (mAb) and either a whole body irradiation (WBI)- or cyclophosphamide (CPP)-based immunosuppressive regimen.