Open AccessPRETRANSPLANT DONOR-SPECIFIC HELPER T CELL REACTIVITY AS A TOOL FOR TAILORING THE INDIVIDUAL NEED FOR IMMUNOSUPPRESSION1
Author(s) -
van der Mast Bj,
van Besouw Nm,
de Kuiper P,
Vaessen Lm,
Gregoor Pj,
Ijzermans Jn,
van Gelder T,
Claas Fh,
Willem Weimar
Publication year - 2001
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200109150-00023
Subject(s) - toxoid , transplantation , cytotoxic t cell , immunology , lymphocyte , peripheral blood mononuclear cell , medicine , mixed lymphocyte reaction , antigen , t lymphocyte , immune system , tetanus , t cell , in vitro , chemistry , vaccination , immunization , biochemistry
A reliable immunological assay for quantification of donor-specific alloreactivity to identify patients at risk for future allograft rejection would be a helpful tool in organ transplantation. Therefore, we questioned whether the T cell reactivity in patients measured before transplantation was predictive for the occurrence of acute rejection during the first year after kidney transplantation.