Open AccessAPOPTOSIS AND CHEMOKINE INDUCTION AFTER RENAL ISCHEMIA-REPERFUSION1
Author(s) -
M.A.R.C. Daemen,
Bart de Vries,
Cornelis van ‘t Veer,
Tim G. A. M. Wolfs,
Wim A. Buurman
Publication year - 2001
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200104150-00032
Subject(s) - chemokine , apoptosis , inflammation , kidney , ischemia , myeloperoxidase , renal ischemia , medicine , pharmacology , immunology , caspase 3 , reperfusion injury , chemistry , endocrinology , biochemistry , programmed cell death
One of the earliest prerequisites for the development of inflammation after ischemia-reperfusion (I/R) is local chemokine expression. We recently demonstrated that apoptosis, characterized by intracellular caspase-activation, contributes to the development of inflammation after I/R.