Open AccessFINE-NEEDLE ASPIRATION BIOPSY ALLOWS EARLY DETECTION OF ACUTE REJECTION IN CHILDREN AFTER RENAL TRANSPLANTATION 1
Author(s) -
Maria Their,
von Willebrand E,
Eero Taskinen,
Kai Rönnholm,
Christer Holmberg,
Hannu Jalanko
Publication year - 2001
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200103270-00008
Subject(s) - medicine , methylprednisolone , creatinine , biopsy , transplantation , urine , surgery , urology
analysis detected rejections often before clinical signs. Half of the patients had increased serum creatinine concentration and 38% had fever at the time of rejection diagnosis. Both signs were present in only 19% of the episodes. A decrease in urine output (>20%) was seen in a third of the episodes. The rejections responded well to oral methylprednisolone (3 mg/kg/day), and lymphoglobulins were needed in only 12% of the episodes. More than 90% of the rejections were completely reversible and no transplant was lost because of acute rejection.