Open AccessANTI-GAL ANTIBODIES IN HUMANS AND 1, 3??-GALACTOSYLTRANSFERASE KNOCK-OUT MICE1
Author(s) -
Tsu Rong Chiang,
Laurent Fanget,
Richard C. Gregory,
Yong Tang,
Denis Luc Ardiet,
Lan Gao,
Carol Meschter,
Alan P. Kozikowski,
Roland Buelow,
Wim M.J. Vuist
Publication year - 2000
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200006270-00020
Subject(s) - antibody , isotype , avidity , epitope , xenotransplantation , microbiology and biotechnology , biology , immunology , chemistry , monoclonal antibody , transplantation , medicine
Due to the absence of alphaGAL epitopes, humans and galactosyltransferase knock-out (GALT/ KO) mice express high levels of anti-Gal antibodies. We describe the properties of mouse anti-GAL antibodies.