Open AccessROLE OF PORCINE P-SELECTIN IN COMPLEMENT-DEPENDENT ADHESION OF HUMAN LEUKOCYTES TO PORCINE ENDOTHELIAL CELLS
Author(s) -
Scott A. Rollins,
Krista Johnson,
Lan Li,
Carl Birks,
Louis A. Matis,
Russell P. Rother
Publication year - 2000
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200004270-00023
Subject(s) - l selectin , microbiology and biotechnology , transfection , neuraminidase , recombinant dna , selectin , p selectin , endothelial stem cell , cell adhesion , complement system , e selectin , in vitro , endothelium , biology , cell adhesion molecule , cell culture , chemistry , immunology , cell , antibody , biochemistry , platelet , gene , platelet activation , endocrinology , genetics , virus
Rapid leukocyte adherence to donor organ vasculature is a hallmark of hyperacute xenograft rejection. However, the molecular interactions required for leukocyte binding to vascular endothelium have not been characterized.