Open AccessCLINICOPATHOLOGICAL ANALYSIS OF LIVER ALLOGRAFT BIOPSIES WITH LATE CENTRILOBULAR NECROSIS
Author(s) -
Yūichi Nakazawa,
Neal I. Walker,
Paul Kerlin,
Charles Steadman,
Stephen V. Lynch,
Russell W. Strong,
Andrew D. Clouston
Publication year - 2000
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200004270-00014
Subject(s) - centrilobular necrosis , medicine , necrosis , pathology , liver transplantation , transplantation
Centrilobular necrosis (CLN) in liver allografts can be a difficult lesion to interpret histologically. Although long recognized in association with developing chronic rejection, recent studies have described the lesion in association with a number of other disease processes. To clarify the histologic features that could allow a specific diagnosis to be made and to determine the outcome in different diagnostic groups, we assessed biopsies from 54 patients with CLN.