Open AccessGENETIC SUSCEPTIBILITY TO RENAL ISCHEMIA REPERFUSION INJURY REVEALED IN A MURINE MODEL
Author(s) -
Melissa J. Burne,
Mahmudul Haq,
Hiroto Matsuse,
Shyam S. Mohapatra,
Hamid Rabb
Publication year - 2000
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200003150-00065
Subject(s) - creatinine , medicine , blood urea nitrogen , kidney , endocrinology , immunology
The development of genetically engineered mice has led to increased use of mouse models to study renal ischemic reperfusion injury (IRI). We hypothesized that susceptibility to IRI could result from strain differences due to genetic factors.