Open AccessIN VIVO T-CELL DEPLETION ENHANCES PRODUCTION OF ANTI-GAL??1,3GAL NATURAL ANTIBODIES IN ??1,3-GALACTOSYLTRANSFERASE-DEFICIENT MICE1
Author(s) -
Hideki Ohdan,
YongGuang Yang,
Kirsten G. Swenson,
Aron Thall,
Megan Sykes
Publication year - 2000
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200003150-00041
Subject(s) - in vivo , antibody , galactosyltransferase , immunology , chemistry , biology , biochemistry , enzyme , genetics
It has been reported that T-cell depletion by in vivo treatment with monoclonal antibodies results in polyclonal B-cell activation. However, its effects on B cells responding to Galalpha1,3Gal (Gal) epitopes remain unknown.