Open AccessBILE ACIDS IN XENOGENEIC EX-VIVO LIVER PERFUSION
Author(s) -
David P. Foley,
Bradley R. Collins,
John C. Magee,
Jeffrey L. Platt,
Elizer Katz,
Robert C. Harland,
William C. Meyers,
Ravi S. Chari
Publication year - 2000
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-200001270-00009
Subject(s) - bile acid , perfusion , ex vivo , fulminant hepatic failure , in vivo , liver transplantation , medicine , gastroenterology , transplantation , biology , microbiology and biotechnology
In recent years, hepatic support systems using xenogeneic cells have been developed to support patients in fulminant hepatic failure. The extent to which xenogeneic hepatocytes metabolize and excrete human organic anions is unclear. In these studies we examined the ability of the ex vivo porcine liver to clear human bile acids during extracorporeal liver perfusion (ELP).