Open AccessACQUIRED PROTEIN S DEFICIENCY WITH MULTIPLE THROMBOTIC COMPLICATIONS AFTER ORTHOTOPIC LIVER TRANSPLANT
Author(s) -
Scott M. Schuetze,
Michael Linenberger
Publication year - 1999
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-199905270-00013
Subject(s) - medicine , liver transplantation , orthotopic liver transplantation , thrombosis , protein s deficiency , protein c deficiency , anticoagulant , coagulopathy , protein c , protein s , transplantation , gastroenterology , factor v leiden , immunology , venous thrombosis
Orthotopic liver transplantation (OLT) is frequently complicated by thrombotic events that may threaten the viability of the allograft and severely compromise the overall outcome in these patients. Although multiple prothrombotic pathogenic mechanisms may be involved, a role for inadequate natural anticoagulant levels in the early postoperative period has been postulated.