Open AccessMALONONITRILAMIDES (MNAs) EXERT THEIR IMMUNOSUPPRESSIVE ACTIVITY PRIMARILY BY INHIBITION OF DIHYDROOROTATE DEHYDROGENASE (DHODH).
Author(s) -
H. U. Schorlemmer,
U. Milbert,
R. Schleyerbach,
Barry B. Kirschbaum
Publication year - 1999
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-199904150-00244
Subject(s) - dihydroorotate dehydrogenase , pyrimidine metabolism , leflunomide , pyrimidine , intracellular , transplantation , cytidine , nucleotide , in vitro , mechanism of action , uridine , biochemistry , cell growth , cell culture , chemistry , biology , enzyme , rna , medicine , purine , immunology , genetics , methotrexate , gene