Open AccessHEMOPHAGOCYTOSIS: A POTENTIAL COMPLICATION IN SMALL BOWEL TRANSPLANTATION
Author(s) -
Paolo Muiesan,
Anil Dhawan,
Jules Wendon,
Ghulam J. Mufti,
John O’Grady,
Mohamed Rela,
Nigel Heaton
Publication year - 1998
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-199809270-00015
Subject(s) - hemophagocytosis , medicine , pancytopenia , histiocytosis , histiocyte , transplantation , immunology , hepatosplenomegaly , systemic lupus erythematosus , pathology , bone marrow , disease
Acquired hemophagocytosis is a histiocytic proliferation associated with phagocytosis of the hemopoietic elements resulting in fever, profound pancytopenia, hepatosplenomegaly, lymphadenopathy, and coagulopathy. Acquired hemophagocytic syndrome is a specific entity that can be differentiated from malignant histiocytosis and familial hemophagocytosis. It has been associated with a variety of disorders, including immunodeficiency, infection, hemopathies, cancer, and autoimmune diseases, as well as with the period following solid organ and bone marrow transplantation.