Open AccessTHE CELLULAR BASIS OF CARDIAC ALLOGRAFT REJECTION
Author(s) -
Steven Merten,
Ju Chuan Chen,
Hong Koo Ha,
Karren M. Plain,
Rochelle Boyd,
Mark J. Penny,
Peter L. Leenaerts,
Bruce M. Hall
Publication year - 1998
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-199805150-00002
Subject(s) - granzyme b , cd8 , perforin , cytotoxic t cell , immunology , t cell , granzyme , cytokine , tumor necrosis factor alpha , major histocompatibility complex , granzyme a , biology , immune system , biochemistry , in vitro
The delayed allograft rejection in C6-deficient PVG C6- rats compared with normal PVG rats has been attributed to the lack of alloantibody activation of the membrane attack complex of complement. As T cells alone have been shown to effect graft rejection, we examined T-cell responses in PVG C6- rats.