Open AccessRECOGNITION OF MAJOR HISTOINCOMPATIBILITIES AFTER TRANSPLANTATION WITH MARROW FROM HLA CLOSELY MATCHED DONORS1
Author(s) -
Nathalie Rufer,
Claudine Helg,
JeanMarie Tiercy,
Catherine Barbey,
Aloïs Gratwohl,
Chapuis Bernard,
M Jeannet,
Eddy Roosnek
Publication year - 1997
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-199706270-00022
Subject(s) - cytotoxic t cell , human leukocyte antigen , antigen , immunology , transplantation , bone marrow , histocompatibility testing , medicine , histocompatibility , graft versus host disease , biology , in vitro , genetics
To determine the extent to which major histoincompatibilities are recognized after bone marrow transplantation, we characterized the specificity of the cytotoxic T lymphocytes isolated during graft-versus-host disease. We studied three patients transplanted with marrow from donors who were histoincompatible for different types of HLA antigens.