Open AccessLATE MORTALITY AND MORBIDITY FIVE TO EIGHTEEN YEARS AFTER KIDNEY TRANSPLANTATION
Author(s) -
C Toussaint,
Paul Kinnaert,
Pierre Vereerstraeten
Publication year - 1988
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-198803000-00010
Subject(s) - medicine , sepsis , dialysis , surgery , transplantation , incidence (geometry) , kidney transplantation , physics , optics
The experience with 102 kidney transplants (86 from cadaver donors) functioning more than 5 years in 99 patients followed in one center is reviewed. With the 100% survival point set at 5 years, patient and graft survivals were 92% and 73% at 10 years, and 70% and 56% at 15 years, respectively. Of those 102 recipients, 58 are presently alive with a functioning graft and 18 died with a functioning graft; 26 patients rejected their graft after a mean interval of 8.3 years posttransplant, 11 of them died within 4-45 months following readmission to dialysis. For the whole group, 29 patients died after a mean period of 10 years following transplantation. Main causes of death were vascular catastrophes (48%), malignancies (21%), sepsis (17%), and liver failure (14%). Because vascular accidents, hepatic failure, and sepsis predominated in male patients, the overall late mortality was higher in male (37%) than in female (25%) patients. The high incidence of late complications--including chronic and acute graft rejections--in long-term kidney recipients constitutes a strong argument for maintaining constant supervision of those patients by a medical team with extensive experience with transplantation.