Open AccessTRANSPLANTATION REACTIONS IN THE AFRICAN LUNGFISH, PROTOPTERUS AMPHIBIUS
Author(s) -
Richard Haas
Publication year - 1982
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-198203000-00008
Subject(s) - lungfish , biology , transplantation , histocompatibility , zoology , major histocompatibility complex , fish <actinopterygii> , immunology , antigen , medicine , fishery , human leukocyte antigen
Wild caught African lungfish, Protopterus amphibius, were found to reject most first-set cutaneous allografts more slowly than comparable allograft rejection in teleost fishes at a temperature of 24.0 +/- 0.5 C. Second-set allografts made 68 days after first sets were rejected more rapidly, indicating the immunological basis for rejection in this primitive fish. Wide variation in survival times of scale transplants with some surviving in excess of 131 days suggest moderate histoincompatibility systems and substantial sharing of histocompatibility antigens.