Open AccessRECURRENT IDIOPATHIC MEMBRANOUS GLOMERULONEPHRITIS
Author(s) -
Robert J. Rubin,
Vivian W. Pinn,
Benjamin A. Barnes,
John T. Harrington
Publication year - 1977
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/00007890-197707000-00002
Subject(s) - glomerulonephritis , membranous nephropathy , nephrotic syndrome , medicine , transplantation , pathological , pathology , immunofluorescence , immunology , kidney , gastroenterology , antibody
This study reports the clinical and pathological findings in a patient with recurrent membranous glomerulonephritis following transplantation of an HLA-identical kidney. Such a recurrence has been previously reported only once, although membranous glomerulonephritis is a common cause of nephrotic syndrome in adults. This case confirms that membranous glomerulonephritis may occasionally recur following renal transplantation and demonstrates that immunofluorescence and electron microscopic studies may be necessary to distinguish recurrent, membranous glomerulonephritis from the membranous changes frequently seen with chronic rejection. In light of the apparent low incidence of recurrent membranous glomerulonephritis, renal transplantation remains an excellent therapeutic option in this disease.