Open AccessMycoplasma hominis and Ureaplasma species brain abscess in a neonate
Author(s) -
Rohit Rao,
Nancy S. Ghanayem,
Bruce A. Kaufman,
K. Sue Kehl,
David C. Gregg,
Michael J. Chusid
Publication year - 2002
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/00006454-200211000-00026
Subject(s) - doxycycline , medicine , mycoplasma hominis , ureaplasma , mycoplasmataceae , ureaplasma urealyticum , brain abscess , meningitis , mycoplasma , mollicutes , erythromycin , cerebrospinal fluid , microbiology and biotechnology , central nervous system , abscess , antibiotics , pathology , surgery , biology
We report an infant with a mixed Mycoplasma and Ureaplasma brain abscess who was successfully treated with intravenous doxycycline and erythromycin. Therapeutic concentrations of doxycycline were demonstrated in cerebrospinal fluid. This report is evidence of the potential for Mycoplasma and Ureaplasma to produce focal central nervous system infection, as well as meningitis, in neonates and that use of doxycycline can be efficacious in the therapy of such infections.