Open AccessNo effect of a noradrenergic reuptake inhibitor on performance in trained cyclists
Author(s) -
Maria Francesca Piacentini,
Romain Meeusen,
Luk Buyse,
Guido De Schutter,
Farid Kempenaers,
Joeri Van Nijvel,
Kenny De Meirleir
Publication year - 2002
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1097/00005768-200207000-00021
Subject(s) - placebo , reboxetine , medicine , analysis of variance , endocrinology , reuptake inhibitor , serotonin reuptake inhibitor , statistical significance , psychology , prolactin , time trial , hormone , serotonin , blood pressure , heart rate , alternative medicine , receptor , pathology
According to the central fatigue hypothesis, serotonin (5-HT) is related to fatigue, whereas the noradrenergic system is primarily concerned with arousal and motivation, and therefore hypothesized to enhance performance. The purpose of the present study was to examine the effects of a selective noradrenergic reuptake inhibitor (reboxetine 2 x 4 mg REB-NARI) on exercise performance.