Open AccessTraining down-regulates fatty acid synthase and body fat in obese Zucker rats
Author(s) -
R. Fiebig,
John M. Hollander,
Denise M. Ney,
R. A. Boileau,
Elizabeth H. Jeffery,
Li Li Ji
Publication year - 2002
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1097/00005768-200207000-00009
Subject(s) - medicine , endocrinology , fatty acid synthase , lipogenesis , hyperinsulinemia , meal , fatty acid , chemistry , fatty liver , obesity , metabolism , insulin resistance , lipid metabolism , biochemistry , disease
The purpose of this study was to investigate whether chronic exercise training attenuates fatty acid synthase, the rate-limiting enzyme for hepatic lipogenesis, and the accumulation of body fat by using obese Zucker rats (OZR) as a model.