Open AccessSkeletal muscle oxidative capacity and exercise tolerance in rats with heart failure
Author(s) -
Philipp Pfeifer,
Timothy I. Musch,
R. M. McAllister
Publication year - 2001
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1097/00005768-200104000-00006
Subject(s) - skeletal muscle , heart failure , oxidative phosphorylation , cardiology , medicine , physical medicine and rehabilitation , chemistry , biochemistry
Past research has shown the development of exercise intolerance after myocardial infarction (MI). The purpose of this study was to test the hypothesis that reductions in oxidative enzyme activity, in a variety of skeletal muscles, coincide with the development of exercise intolerance in a rat model of chronic heart failure (CHF) induced by MI.