Open AccessSwimming training prevents generation of suppressor macrophages during acute cold stress
Author(s) -
Takako Kizaki,
Shukoh Haga,
Isao Sakata,
Tomomi Ookawara,
M Segawa,
Takeshi Sakurai,
Tetsuya Izawa,
Hideki Ohno
Publication year - 2000
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1097/00005768-200001000-00021
Subject(s) - splenocyte , cold stress , endocrinology , medicine , population , glucocorticoid receptor , glucocorticoid , immunology , biology , chemistry , antibody , biochemistry , environmental health , gene
Acute cold stress induces suppressor macrophages expressing large numbers of receptors to Fc portion of immunoglobulin G (MAC-1+ Fc gammaRII/IIIbright cells), resulting in suppression of splenocyte mitogenesis. The generation of MAC-1+ Fc gammaRII/IIIbright cells is partly mediated by increased glucocorticoid levels during acute cold stress. The aim of the current study was to investigate the effect of swimming training on the generation of the MAC-1+ Fc gammaRII/IIIbright suppressor macrophages by acute cold stress.