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Swallowing‐Related Quality of Life After Head and Neck Cancer Treatment
Author(s) -
Gillespie M Boyd,
Brodsky Martin B.,
Day Terry A.,
Lee FuShing,
MartinHarris Bonnie
Publication year - 2004
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/00005537-200408000-00008
Subject(s) - medicine , dysphagia , swallowing , head and neck cancer , larynx , radiation therapy , quality of life (healthcare) , laryngectomy , cancer , pharynx , surgery , nursing
Objectives: To determine the role of treatment modality in swallowing outcome after head and neck cancer treatment and to identify potential risk factors for posttreatment dysphagia. Study Design: Cross‐sectional survey of patients with no evidence of disease 12 months or more after the treatment of a stage III or IV squamous cell carcinoma of the oropharynx, larynx, or hypopharynx. Methods: Potential subjects were stratified by tumor site and tumor T‐stage to achieve a balanced comparison between chemoradiation (n = 18) and surgery/radiation (n = 22) groups. Outcome measures included a dysphagia risk factor survey, the MD Anderson Dysphagia Inventory (MDADI), and the Short‐Form 36 (SF‐36). Results: Patients who received chemoradiation for oropharyngeal primaries demonstrated significantly better scores on the emotional ( P = .03) and functional ( P = .02) subscales of the MDADI than did patients who underwent surgery followed by radiation. There were no significant differences between chemoradiation and surgery/radiation groups for laryngeal and hypopharyngeal primaries. Additional risk factors for posttreatment dysphagia include prolonged (>2 weeks) nothing by mouth (NPO) status ( P = .002) and low SF‐36 Mental Health Subscale score ( P = .002). Conclusion: The study suggests that chemoradiation may provide superior swallowing outcome to surgery/radiation in patients with oropharyngeal primary. Patients with depressed mental health and prolonged feeding tubes may be at higher risk of long‐term dysphagia.