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Total Glossectomy Without Laryngectomy as First‐Line or Salvage Therapy
Author(s) -
Barry Béatrix,
Baujat Bertrand,
Albert Sébastien,
Nallet Emmanuel,
Depondt Joël,
Guedon Charles,
Gehanno Pierre
Publication year - 2003
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/00005537-200302000-00031
Subject(s) - medicine , laryngectomy , glossectomy , surgery , retrospective cohort study , tongue , radiation therapy , salvage therapy , osteoradionecrosis , cohort , larynx , chemotherapy , pathology
Objectives/Hypothesis Advanced carcinoma of the tongue can require total glossectomy. Although radiation therapy is of limited efficacy in T3 and T4 tumors involving the base of the tongue, many surgeons are reluctant to suggest highly mutilating surgery. Study Design Retrospective cohort study. Methods We compared early postoperative complications, hospital stay duration, function, and oncological outcomes in patients who underwent total glossectomy without laryngectomy as first‐line or salvage therapy. Results Postoperative course and functional outcomes were similar in the two groups. Overall survival was 32% at 3 years and 21% at 5 years. The risk factors for shorter survival were positive margins of resection ( P = .002) and tumor spread into the mandible ( P = .04). Salvage surgery was not associated with significantly lower survival ( P = .09 [NS]). Conclusions Postoperative morbidity and functional outcomes are similar after first‐line and salvage total glossectomy without laryngectomy. Local tumor control is the main factor influencing survival.