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Relief of Post‐Tonsillectomy Pain by Release of Lidocaine From Fibrin Glue
Author(s) -
Kitajiri Shinichiro,
Tabuchi Keisaku,
Hiraumi Harukazu,
Kaetsu Hiroshi
Publication year - 2001
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/00005537-200104000-00015
Subject(s) - tonsillectomy , medicine , analgesic , anesthesia , lidocaine , surgery , fibrin glue , fibrin , group b , tonsil , local anesthesia , immunology
Objectives Pain inevitably develops after resection of the palatine tonsil (tonsillectomy). Therefore, we applied a mixture of lidocaine and fibrin glue to the tonsillar fossae immediately after tonsillectomy and evaluated its analgesic effects. Study Design A prospective randomized trial. Methods Seventy‐four consecutive patients who had undergone tonsillectomy by the same surgeon (S.K.) were allocated by the sealed envelope method into three groups. After routine tonsillectomy, the operation was terminated in group A (control group), but the bilateral tonsillar fossae were covered with 1 mL fibrin glue using CaCl 2 as solution to dissolve thrombin in group B and using 4% lidocaine chloride instead of CaCl 2 in group C. No significant difference was observed in age or sex among the three groups. Analgesic effects were evaluated in terms of the postoperative days required until the patient began to eat normally and the postoperative days on which the patient desired analgesic administration. Results The mean postoperative days until the patient began to eat normally were 4.22 in group A and 3.78 in group B, showing no significant difference, but 2.83 in group C, being significantly shorter ( P <.05). The mean postoperative days on which analgesic administration was necessary were 4.56 in group A and 4.91 in group B, showing no significant difference, but 2.88 in group C, being significantly shorter ( P <.05). Conclusion This method can be readily performed, requires no special treatment, and appears to have adequate pain‐relieving effects.