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Meta‐Analysis of Outcomes of Pediatric Functional Endoscopic Sinus Surgery
Author(s) -
Hebert Richard L.,
Bent John P.
Publication year - 1998
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/00005537-199806000-00004
Subject(s) - medicine , functional endoscopic sinus surgery , inclusion and exclusion criteria , sinusitis , meta analysis , cystic fibrosis , surgery , endoscopic sinus surgery , pediatrics , pathology , alternative medicine
Objective: To create a consensus of outcomes of pediatric functional endoscopic sinus surgery (FESS) and assess its effectiveness and safety. Study Design: A meta‐analysis of the literature on outcomes of pediatric FESS. Methods: A meta‐analysis of the literature was performed focusing on the number of patients per study, length of follow‐up, prospective versus retrospective, and the separation or exclusion of patients with significant underlying systemic diseases (cystic fibrosis and immunodeficiencies). A rating scale based on the above criteria was used to select articles for inclusion. Results: Eight published articles (832 patients) plus unpublished data from the authors' institution (50 patients) were included. The “positive” outcome rates for published, unpublished, and combined data were 88.4%, 92%, and 88.7%, respectively. No statistically significant differences in “positive” outcome existed between all published or unpublished series using a chi‐squared test (power = .51, P = .38). The average combined follow‐up was 3.7 years, with a major complication rate of 0.6%. Conclusion: Pediatric FESS is a safe and effective treatment for chronic sinusitis that is refractory to medical therapy.