Premium
Nasal Septal Squamous Cell Carcinoma: A Chart Review and Meta‐analysis
Author(s) -
DiLeo Michael D.,
Miller Robert H.,
Rice Janet C.,
Butcher R. Brent
Publication year - 1996
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/00005537-199610000-00008
Subject(s) - medicine , basal cell , stage (stratigraphy) , nasal septum , radiation therapy , meta analysis , carcinoma , cancer , presentation (obstetrics) , surgery , oncology , dermatology , nose , paleontology , biology
Squamous cell carcinoma of the nasal septum occurs infrequently and is often misdiagnosed because its symptoms are similar to everyday rhinologic complaints. The published series have been too small to determine the best form of treatment for this cancer. The authors of this study retrospectively reviewed nasal septal squamous cell carcinomas treated at three university‐affiliated hospitals over a 30‐year period. Sixteen primary tumors were identified and reviewed for presentation, staging, treatment, recurrence patterns, and risk factors. The authors then combined their findings with those of suitable literature series and performed a meta‐analysis to evaluate predictors of survival. There were too few patients in each stage and treatment group to significantly determine the optimal treatment for nasal septal squamous cell carcinoma. However, based on the present study and the literature series, the authors suggest that small lesions may be confidently treated with either radiation or surgery and that combined therapy may be reserved for more advanced tumors. Laryngoscope, 106:1218‐1222, 1996