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Extranodal Rosai‐Dorfman Disease of the Head and Neck
Author(s) -
Goodnight James W.,
Wang Marilene B.,
Sercarz Joel A.,
Fu Yao S.
Publication year - 1996
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/00005537-199603000-00002
Subject(s) - medicine , rosai–dorfman disease , paranasal sinuses , histopathology , histiocyte , pathology , head and neck , nose , cervical lymphadenopathy , disease , confusion , radiology , surgery , psychology , psychoanalysis
Rosai‐Dorfman disease is a rare, idiopathic, benign histiocytic proliferation usually seen in younger patients. Massive lymphadenopathy most commonly involves the cervical lymph nodes, with a predominant infiltration of sinusoidal histiocytes. Nearly half of the patients will have extranodal involvement, 75% occurring in sites in the head and neck. Three cases of extranodal Rosai‐Dorfman disease of the head and neck involving the nose, paranasal sinuses, and parotid gland are presented. The clinical presentation, histologic characteristics, radiographic findings, and treatment of the disease are discussed. Because of the scarcity of cases, the clinical and histopathologic features of this disease may be overlooked. Familiarity with its relatively frequent clinical manifestations in the head and neck, as well as with the diagnostic histopathology, should preclude confusion with other disease entities.