Open AccessSynthetic Human α-Atrial Natriuretic Peptide Improves the Management of Postoperative Hypertension and Renal Dysfunction after the Repair of Abdominal Aortic Aneurysm
Author(s) -
Yoshitaka Hayashi,
Masakatsu Ohtani,
Yoshiki Sawa,
Taizo Hiraishi,
Hitoshi Akedo,
Yasuhiko Kobayashi,
Hikaru Matsuda
Publication year - 2003
Publication title -
journal of cardiovascular pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.762
H-Index - 100
eISSN - 1533-4023
pISSN - 0160-2446
DOI - 10.1097/00005344-200311000-00009
Subject(s) - medicine , atrial natriuretic peptide , abdominal aortic aneurysm , furosemide , aortic aneurysm , aneurysm , abdominal aorta , anesthesia , aorta , cardiology , urology , endocrinology , surgery
Delayed hypertension (HT) and renal dysfunction (RD) are observed after aortic operations accompanied by infra-renal aortic cross-clamping (AXC). Atrial natriuretic peptide (ANP) has effects on vasodilation and renal protection, and we examined the hypothesis that synthetic human alpha-ANP (hANP) improves the postoperative management for abdominal aortic aneurysm (AAA).