Open AccessHuman Antichimeric Antibody in Children and Young Adults with Inflammatory Bowel Disease Receiving Infliximab
Author(s) -
Erasmo Miele,
Jonathan E. Markowitz,
Petar Mamula,
Robert N. Baldassano
Publication year - 2004
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/00005176-200405000-00008
Subject(s) - medicine , infliximab , concomitant , ulcerative colitis , inflammatory bowel disease , gastroenterology , antibody , antibody titer , titer , disease , immunology
Pediatric studies on immunogenicity of infliximab have not been published. The aim of the study was to evaluate the prevalence of human antichimeric antibody (HACA), relationship to infusion reactions (IR), and the role of concomitant immunomodulatory therapies.