Open AccessEnergy Supplements Rich in Linoleic Acid Improve Body Weight and Essential Fatty Acid Status of Cystic Fibrosis Patients
Author(s) -
Gratiana Steinkamp,
Hans Demmelmair,
Ina RühlBagheri,
H. von der Hardt,
Berthold Koletzko
Publication year - 2000
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/00005176-200010000-00016
Subject(s) - medicine , linoleic acid , steatorrhea , essential fatty acid , polyunsaturated fatty acid , underweight , phospholipid , arachidonic acid , fatty acid , weight loss , gastroenterology , endocrinology , overweight , obesity , biochemistry , chemistry , enzyme , membrane
Patients with cystic fibrosis who have steatorrhea frequently are underweight and have essential fatty acid (EFA) depletion, which is associated with a poor clinical course. It has been stated that poor EFA status is difficult to correct in patients with cystic fibrosis, and an impaired EFA metabolism with reduced synthesis of long-chain polyunsaturated fatty acids has been proposed. In this study, the effects of an oral energy supplement rich in linoleic acid were investigated in patients with cystic fibrosis who had a body weight below 95% of normal for height.