Open AccessDietary Modulation of Intestinal Fructose Transport and GLUT5 mRNA Expression in Hypothyroid Rat Pups
Author(s) -
Iona M. Monteiro,
Lan Jiang,
Ronaldo P. Ferraris
Publication year - 1999
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/00005176-199911000-00017
Subject(s) - endocrinology , medicine , fructose , weaning , euthyroid , biology , thyroid , biochemistry
Intestinal fructose transport rates or GLUT5 mRNA levels typically show a two- to threefold increase after weaning in rats allowed to wean normally but can be enhanced precociously by high-fructose diets during early weaning. Developmental increases in serum thyroxine levels coincide with the onset of weaning and have been linked to changes in intestinal sucrase and lactase activities.