Open AccessEvaluation of Serology, 13C-Urea Breath Test, and Polymerase Chain Reaction of Stool Samples to Detect Helicobacter pylori in Bangladeshi Children
Author(s) -
Thomas Casswall,
HansOlof Nilsson,
Mats Bergström,
Pär Aleljung,
Torkel Wadström,
Anders Dahlström,
M. John Albert,
Shafiqul Alam Sarker
Publication year - 1999
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/00005176-199901000-00009
Subject(s) - serology , medicine , helicobacter pylori , breath test , concordance , immunoassay , urea breath test , gold standard (test) , polymerase chain reaction , gastroenterology , immunomagnetic separation , immunology , antibody , helicobacter pylori infection , biology , microbiology and biotechnology , biochemistry , gene
Serologic methods to detect Helicobacter pylori in infants, especially in developing countries, may be limited because of decreased immune response caused by malnutrition. The true prevalence may therefore be underestimated in this age group. Urea breath test is considered to be a good screening method in children but is expensive and therefore is not suitable for screening in developing countries. Simple, inexpensive, and accurate noninvasive methods to detect H. pylori in infants and young children are needed.