Open AccessLuminal Stability of Insulin-Like Growth Factors I and II in Developing Rat Gastrointestinal Tract
Author(s) -
R. K. Rao,
Anthony F Philipps,
Catherine S. Williams,
D. M. McCracken,
Otakar Koldovský
Publication year - 1998
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/00005176-199802000-00012
Subject(s) - endocrinology , medicine , receptor , jejunum , insulin like growth factor , incubation , small intestine , in vitro , lumen (anatomy) , growth factor , biology , biochemistry
Insulin-like growth factors (IGF)-I and -II are present in milk of a number of mammalian species. The stability of IGF-I and -II in the intestinal lumen was investigated by measuring the proteolytic degradation of 125I-labeled IGF-I and IGF-II by rat (suckling and adult) intestinal luminal flushings in vitro.