Open AccessAngiotensin II-induced apoptosis in rat cardiomyocyte culture: a possible role of AT1 and AT2 receptors
Author(s) -
Ilan Goldenberg,
Ehud Grossman,
Kenneth A. Jacobson,
Vladimir Shneyvays,
Asher Shainberg
Publication year - 2001
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/00004872-200109000-00022
Subject(s) - angiotensin ii , angiotensin ii receptor type 1 , tunel assay , irbesartan , verapamil , apoptosis , endocrinology , medicine , angiotensin receptor , intracellular , biology , receptor , calcium , microbiology and biotechnology , biochemistry , blood pressure
To investigate the mechanism of angiotensin II-induced apoptosis in cultured cardiomyocytes by determining which receptor subtype is involved, and what is the relationship between intracellular Ca2+ changes and apoptosis.