Open AccessSkeletal Muscle Lipid and Its Association with Insulin Resistance: What Is the Role for Exercise?
Author(s) -
Bret H. Goodpaster,
Nicholas F. Brown
Publication year - 2005
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/00003677-200507000-00008
Subject(s) - insulin resistance , skeletal muscle , resistance training , medicine , endocrinology , insulin , association (psychology) , psychology , psychotherapist
Skeletal muscle lipid content has been associated with insulin resistance and type 2 diabetes. However, intramuscular triglycerides can also be a fuel source for healthy muscle during exercise. The balance between storage and use of muscle triglycerides is likely a key to the interaction between dysregulated fat and glucose metabolism by healthy and insulin resistant muscle.