Open AccessIs There a Link between Malignant Hyperthermia and Exertional Heat Illness?
Author(s) -
Sheila M. Muldoon,
Patricia A. Deuster,
Barbara W. Brandom,
Rolf Bϋnger
Publication year - 2004
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/00003677-200410000-00009
Subject(s) - malignant hyperthermia , heat illness , hyperthermia , medicine , ryanodine receptor , receptor , anesthesia , physics , meteorology
Exertional heat illness (EHI) and malignant hyperthermia (MH) are two potentially lethal conditions. It has been suggested that a subset of MH susceptible persons may be predisposed to EHI. We examine the current understanding of these disorders and explore evidence of a relationship. Screening for the muscle type I ryanodine receptor gene should help clarify the relationship between MH and EHI.