Open AccessSystemic Inflammatory Mediators Contribute to Widespread Effects in Work-Related Musculoskeletal Disorders
Author(s) -
Ann E. Barr,
Mary F. Barbe,
Brian Clark
Publication year - 2004
Publication title -
exercise and sport sciences reviews
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/00003677-200410000-00003
Subject(s) - inflammation , systemic inflammation , medicine , work related musculoskeletal disorders , pathophysiology , affect (linguistics) , fibrosis , immunology , psychology , pathology , human factors and ergonomics , poison control , environmental health , communication
Recent studies in a rat model have indicated that the pathophysiological mechanisms underlying development of work-related musculoskeletal disorders (WMSDs) include widespread inflammation and subsequent fibrosis at high levels of repetition and force. A systemic inflammatory component may affect tissues not directly involved in task performance, thereby contributing to widespread and puzzling symptoms that are often characteristic of patients with WMSDs.