Open AccessMyosin Heavy Chain Expression and Plasticity: Role of Myoblast Diversity
Author(s) -
David Parry
Publication year - 2001
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/00003677-200110000-00008
Subject(s) - myosin , microbiology and biotechnology , myocyte , heavy chain , protein expression , biology , plasticity , biophysics , evolutionary biology , genetics , gene , physics , thermodynamics
Muscle fibers exhibit a limited capacity to alter their myosin heavy chain expression in response to various stimuli. Recent results pertinent to this observation are discussed, and a hypothetical scheme is presented whereby the contribution of myonuclei from distinct populations of myogenic precursors may account for this limited adaptive range.