Open AccessHeartMate III: Pump Design for a Centrifugal LVAD with a Magnetically Levitated Rotor
Author(s) -
Kevin Bourque,
D. Gernes,
H. Loree,
J S Richardson,
Victor L. Poirier,
N. Barletta,
A. Fleischli,
G. Foiera,
Thomas Gempp,
Reto Schoeb,
Kenneth N. Litwak,
Takehide Akimoto,
Mary J. Watach,
Philip Litwak
Publication year - 2001
Publication title -
asaio journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 66
eISSN - 1538-943X
pISSN - 1058-2916
DOI - 10.1097/00002480-200107000-00020
Subject(s) - centrifugal pump , ventricular assist device , thrombogenicity , rotor (electric) , materials science , biomedical engineering , hemolysis , cardiology , mechanical engineering , heart failure , medicine , impeller , engineering , platelet
A long-term, compact left ventricular assist device (LVAD), the HeartMate III, has been designed and fabricated, featuring a centrifugal pump with a magnetically levitated rotor. The pump has been optimized by in vitro testing to achieve a design point of 7 L/min against 135 mm Hg at high hydrodynamic efficiency (30%) and to be capable of up to 10 L/min under such a load. Furthermore, the pump has demonstrated no mechanical failures, low hemolysis (4-10 mg/dl plasma free Hb), and low thrombogenicity during six (40, 27, 59, 42, 27, and 49-day) in vivo bovine studies.