
A Thin-Film Glucose Electrode System with Compensation for Drift
Author(s) -
Yao Sj,
S. Guvench,
Guvench Mg,
Chan Lt,
Robin Ruppel-Kerr,
Marcus Lien,
Wolfson Sk
Publication year - 1989
Publication title -
asaio transactions
Language(s) - English
Resource type - Journals
eISSN - 2375-0952
pISSN - 0889-7190
DOI - 10.1097/00002480-198907000-00186
Subject(s) - compensation (psychology) , electrode , materials science , optoelectronics , chemistry , psychology , psychoanalysis
Thin-film platinum electrodes have been prepared for use in a system for measurement of glucose. Cyclic voltammetry was used to test the electrodes in phosphate and bicarbonate solutions, and in the dialysate of human serum. The peak current output for glucose concentrations between 50-300 mg/dl in a phosphate buffer, and 100-250 mg/dl in the dialysate of human serum, were linear. Two of the three inflection points occurring in the voltammograms are invariant with changes in scan rate, pH, CO2, O2, and glucose. A method for using these points to compensate for voltage drift and current shift is discussed.