Open AccessA New Method of Assessing Left Ventricular Function Under Assisted Circulation Using a Conductance Catheter
Author(s) -
R Matsuwaka,
Hikaru Matsuda,
Susumu Nakano,
R Shirakura,
Mitsunori Kaneko,
Koichi Taniguchi,
Osamu Matsuki,
Takafumi Masai,
Norihide Fukushima,
Yasunaru Kawashima
Publication year - 1989
Publication title -
asaio transactions
Language(s) - English
Resource type - Journals
eISSN - 2375-0952
pISSN - 0889-7190
DOI - 10.1097/00002480-198907000-00090
Subject(s) - circulation (fluid dynamics) , ventricular function , cardiology , catheter , medicine , conductance , mathematics , mechanics , surgery , physics , combinatorics
A new method of assessing left ventricular (LV) systolic function without terminating assisted circulation (AC) was investigated using a LV volume catheter (conductance catheter) in canine cardiopulmonary bypass (CPB) (Group 1, n = 7) and left heart bypass (LHB) (Group 2, n = 5) models. The hearts were subjected to either 20 min of global ischemia (IS), with a subsequent 80 min of reperfusion under CPB, or regional IS under LHB. Instantaneous LV pressure-volume data acquisitions were repeated during transient (15 sec) acute volume loading without terminating bypass. The relationship between the stroke work (SW), determined as the area of the pressure-volume loop, and the end-diastolic volume (EDV), were highly linear at every study point (mean: r = 0.956-0.986 in Group 1, r = 0.974-0.987 in Group 2). The slopes of SW and EDV (preload recruitable stroke work: PRSW) significantly decreased after IS, in both Group 1 and Group 2. In conclusion, measurement of PRSW without terminating bypass seemed to be useful in evaluating LV systolic function in patients under AC.