Open AccessDiffusion- and Perfusion-Weighted Magnetic Resonance Imaging in Human Acute Ischemic Stroke: Technical Considerations
Author(s) -
Yelda Özsunar,
Sorensen Ag
Publication year - 2000
Publication title -
topics in magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 53
eISSN - 1536-1004
pISSN - 0899-3459
DOI - 10.1097/00002142-200010000-00003
Subject(s) - magnetic resonance imaging , diffusion mri , medicine , perfusion , radiology , perfusion scanning , stroke (engine) , diffusion imaging , ischemic stroke , nuclear medicine , ischemia , cardiology , physics , thermodynamics
Diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) are recently developed yet steadily evolving magnetic resonance techniques. DWI and PWI typically interrogate the microscopic diffusion and microcirculatory perfusion, and they can provide early, highly sensitive, and specific delineation of ischemic tissue. These techniques also can play a role in selecting patients who may benefit from thrombolytic therapy. This article reviews physical, technical, and pathophysiological background material that can be helpful in the acquisition and interpretation of DWI and PWI.