Open AccessEffect of antiretroviral drugs on liver fibrosis in HIV-infected patients with chronic hepatitis C
Author(s) -
Juan Macı́as,
V. Castellano,
Nicolás Merchante,
R Palacios,
José A. Mira,
Carmen Sáez,
José A. GarcíaGarcía,
Fernando Lozano,
Jesús GómezMateos,
Juan A. Pineda
Publication year - 2004
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-200403260-00007
Subject(s) - medicine , hepatitis c , chronic hepatitis , human immunodeficiency virus (hiv) , sida , viral disease , liver fibrosis , virology , hepatitis , immunopathology , fibrosis , immunology , virus
The hepatotoxicity of highly active antiretroviral therapy (HAART) could enhance liver fibrosis in HIV/Hepatitis C virus (HCV)-coinfected patients. Moreover, HAART-related immune restoration could lessen HCV-associated liver damage. The data on the effect of protease inhibitors (PI) on liver fibrosis are scant and contradictory. No information is available on the relationship between non-nucleoside analogue therapy and liver fibrosis in co-infected patients.