Open AccessIdentification of two mutually exclusive groups after long-term monitoring of HIV DNA 2-LTR circle copy number in patients on HAART
Author(s) -
John Morlese,
Ian Teo,
Ji-Won Choi,
Brian Gazzard,
Sunil Shaunak
Publication year - 2003
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-200303280-00005
Subject(s) - viral load , drug holiday , lentivirus , virology , peripheral blood mononuclear cell , biology , transmission (telecommunications) , virus , medicine , immunology , viral disease , human immunodeficiency virus (hiv) , genetics , electrical engineering , in vitro , engineering
Anti-retroviral drug therapy reduces but does not abolish HIV transmission and replication throughout the body. HIV DNA 2-long terminal repeat (2-LTR) circles have been shown in point-based studies to persist in some patients whose plasma HIV RNA was undetectable. However, the degree of fluctuation of circle copy number over time has not been determined.