Open AccessThe immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils
Author(s) -
Giovanni Florio,
Angelica Petraroli,
Vincenzo Patella,
Massimo Triggiani,
Gianni Marone
Publication year - 2000
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-200005260-00004
Subject(s) - immunoglobulin e , histamine , superantigen , basophil activation , antibody , glycoprotein , chemistry , immunology , biology , basophil , microbiology and biotechnology , immune system , t cell , pharmacology
To investigate the mechanism whereby HIV-1 envelope glycoprotein gp120 from four different isolates obtained in three different countries induces proinflammatory mediator release from normal human basophils.