Open AccessEffect of ritonavir on lipids and post-heparin lipase activities in normal subjects
Author(s) -
Jonathan Q. Purnell,
Alberto Zambón,
Robert H. Knopp,
David Pizzuti,
Ramanuj Achari,
John M. Leonard,
Charles Locke,
John D. Brunzell
Publication year - 2000
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-200001070-00006
Subject(s) - ritonavir , lipoprotein lipase , medicine , very low density lipoprotein , endocrinology , triglyceride , apolipoprotein b , lipoprotein , cholesterol , hypertriglyceridemia , dyslipidemia , pharmacology , immunology , viral load , human immunodeficiency virus (hiv) , obesity , adipose tissue , antiretroviral therapy
Intensive therapy of HIV infection with highly active antiretroviral therapy (HAART) dramatically reduces viral loads and improves immune status. Abnormalities of lipid levels, body fat distribution, and insulin resistance have been commonly reported after starting HAART. Whether the lipid abnormalities result from changes in metabolism after an improvement in HIV status or are partly attributable to the effects of protease inhibitor use is unknown.