Open AccessInduction of immune responses to HIV-1 by canarypox virus (ALVAC) HIV-1 and gp120 SF-2 recombinant vaccines in uninfected volunteers
Author(s) -
Robert B. Belshe,
Geoffrey J. Gorse,
Mark J. Mulligan,
Thomas G. Evans,
Michael C. Keefer,
JeanLouis Excler,
AnneMarie Duliege,
James Tartaglia,
William I. Cox,
James McNamara,
Kai Hwang,
Alice P. Bradney,
David C. Montefiori,
Kent J. Weinhold
Publication year - 1998
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-199818000-00009
Subject(s) - virology , neutralizing antibody , immunogenicity , cytotoxic t cell , hiv vaccine , antibody , recombinant dna , medicine , immunology , vaccine trial , virus , biology , vaccination , biochemistry , gene , in vitro
To determine the ability of live attenuated canarypox virus expressing HIV antigens to induce CD8+ cytotoxic T-cell responses and to prime for neutralizing antibody responses to boosting with purified recombinant gp120 subunit vaccine.