Open AccessIn vitro selective elimination of HIV-infected cells from peripheral blood in AIDS patients by the immunotoxin DAB389CD4
Author(s) -
Juan Martín-Serrano,
Lola Folgueira,
Laín de Lera T,
Pedraza Ma,
Emmanuel Lemichez,
Sonsoles Sánchez-Palomino,
Noriega Ar,
P Boquet,
José Alcamı́
Publication year - 1998
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/00002030-199808000-00007
Subject(s) - peripheral blood mononuclear cell , immunotoxin , virology , biology , virus , lymphocyte , viral load , trypan blue , in vitro , immunology , cytotoxicity , biochemistry
To study the antiviral efficacy of the recombinant immunotoxin DAB389CD4 against wild-type strains of HIV and to analyse its potential toxicity in non-infected peripheral blood mononuclear cells (PBMC).